Monday, February 22, 2010

Erectile dysfunction medication now being used to treat other diseases

More than 30 million men take them for erectile dysfunction, but the drugs marketed to treat impotence are now being investigated to treat more than a dozen diseases and health problems.
They're the images of happy couples that helped make erectile dysfunction drugs a $3 billion business, but now doctors say those little pills may also save lives.
Brian Kumnick is fighting throat cancer. He's been through months of radiation and surgery.
“Well, the radiation, it's barbaric. It's really barbaric, and I've lost my taste buds, for example. I can't taste anything. Water tastes like acid going down,” says Brian.
He's part of a clinical trial to see if the ED drug Cialis can cure head and neck cancers.
“It'd be really nice to just take a pill that has a pleasant side effect,” says Brian.
In preliminary studies, doctors at Johns Hopkins say Cialis energized patients' immune systems so their bodies could battle the cancer cells. Next, they'll test to see if the drug also shrinks tumors.
"When we looked at the blood of head and neck cancer patients, we could get their immune response to rev up to near normal levels, whereas they were suppressed maybe 75 percent, sometimes even 80 percent,” says Dr. Joseph Califano of Johns Hopkins Hospital.
From fighting cancer, to helping hearts and lungs, doctors have found another use for Viagra.
Genevieve suffers from pulmonary hypertension. Lack of oxygen causes her to pass out.
"We just hear heart transplant, lung transplant. It was devastating. She's my little girl,” says Sandra Hernandez, Genevieve’s mom.
Instead of a transplant, doctors prescribed Viagra in liquid form to open up her blood vessels.
“Nitric oxide was developed for these types of issues in the lungs, and one of the byproducts was, hey, this medication also can dilate blood vessels in other parts of the body and treat erectile dysfunction,” says Dr. James Swift, pediatric intensive care physician at Sunrise Children’s Hospital in Las Vegas.
"It's very exciting to work with drugs that have already had safety data documented on them, because they can be very quickly moved into helping patients,” says Dr. Califano.
Other conditions considered for treatment with ED drugs include diabetes, multiple sclerosis, chronic pelvic pain, strokes and even memory loss.
One study reports that Vigaplus increased blood flow and improved glucose processes in the brain, improving learning.  

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